PDX Biospecimens

JAX is here to support your preclinical oncology research at any stage in your research pipeline. With our large variety of biospecimens, our experts can match you with the most suitable PDX models and services for your research objectives. Our offerings include PDX frozen fragments, PDX unstained slides, and AML splenocytes.

Order Tumor Biospecimens

PDX FFPE Slides - Unstained Single Section

FFPE PDX slides from JAX enable fast and easy screening of your tissue sample for your target of interest. Our formalin-fixed, paraffin-embedded (FFPE) PDX slides provide researchers with access to well-characterized tumor tissue samples for detailed biomarker analysis and target validation studies.

Key Benefits and Advantages:

• Comprehensive Assays: Run immunohistochemical (IHC) or in-situ hybridization (ISH) assays to screen for specific proteins or nucleic acid sequences
• Streamlined Research Workflows and Project Efficiency: Save valuable project time by evaluating your tumor of interest against your target profile before ordering your PDX model
• Rapid Turnaround and Efficient Processing: Perform biomarker assays quickly. Most FFPE slides are shipped within days of your order
• Extensive Library with Comprehensive Coverage: Access FFPE slides that correspond to over 400 PDX models

Order PDX FFPE Slides

PDX Frozen Fragments

JAX provides vials of frozen tumor fragments sourced from our extensive PDX collection. The fragments are non-viable and each vial contains 5 small tumor fragments. Researchers can use comprehensive MMHC database platform to search for and identify available tumor specimens that match their specific research criteria and study requirements.

Key benefits and advantages of the frozen fragments include:

• Microscopic Analysis and Histological Examination: Study the structure and composition of tumors under a microscope, which aids in understanding tumor characteristics and behavior
• Comprehensive Molecular Profiling and Genomic Analysis: Analyze fragments for their DNA, RNA, and protein content, which is crucial for identifying genetic mutations, expression patterns, and other molecular features of tumors
• Biomarker Profiling and Analysis: Identify biomarkers that are indicative of certain types of cancer or responses to treatment

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Passaged AML Splenocyte Samples

Customers can purchase vials of frozen splenocytes from our extensive AML (Acute Myeloid Leukemia) PDX model collection. Each vial contains approximately two million splenocytes with media and DMSO per vial and provides sufficient cell numbers for comprehensive flow cytometry analysis and multiple downstream immunological assays.

Key applications include:

• Comprehensive Immune Profiling and Therapeutic Assessment: Facilitate understanding of immune cell composition and function at the end stages of disease or treatment, which aids in assessing the impact of therapies on the immune system
• Advanced Cytokine Analysis and Immune Response Characterization: Enable measurement of cytokine production, which provides insights into the immune response and inflammation associated with cancer

Learn More about PDX for AML