Cre lines characterized by the JAX Cre Resource
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The Jackson Laboratory Cre Repository uses the following LacZ Staining protocols: | ||||
| Stock number / data sheet | Strain name (links to expression data) |
Promoter (species) | Site of expression | Expression data thumbnail |
|---|---|---|---|---|
| 003574 | B6.Cg-Tg(Alb-cre)21Mgn/J | Alb, albumin (rat) | Liver |  |
| 005359 |
Camk2a, calcium/calmodulin-dependent protein kinase II alpha (mouse) |
Cre recombinase expression is expected in the forebrain, specifically the CA1 pyramidal cell layer in the hippocampus. |
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| 006410 | B6;129S6-Chattm1(cre)Lowl/J | Chat, choline acetyltransferase (mouse) | Cre recombinase activity is reported in all cholinergic neurons. |  |
| 003465 | BALB/c-Tg(CMV-cre)1Cgn/J | CMV, cytomegalovirus (human) | widespread expression, including germline |  |
| 003314 | FVB/N-Tg(EIIa-cre)C5379Lmgd/J | Ella, adenovirus (adenovirus) | widespread expression (including germline); mosaic pattern commonly observed |  |
| 003724 | B6.FVB-Tg(EIIa-cre)C5379Lmgd/J | Ella, adenovirus (adenovirus) | widespread expression (including germline); mosaic pattern commonly observed |  |
| 005628 |
Emx1, empty spiracles homolog 1 (Drosophila) |
neurons of the neocortex and hippocampus, and in the glial cells of the pallium, mimicking the pattern of expression of the endogenous gene |
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| 005069 | B6.Cg-Tg(Fabp4-cre)1Rev/J | Fabp4, fatty acid binding protein 4, adipocyte (mouse) | adipose tissue |  |
| 006084 | Forkhead box G1 (mouse) | telencephalon, anterior optic vesicle (developing lens and retina), otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches |  | |
| 004600 | FVB-Tg(GFAP-cre)25Mes/J | GFAP, glial fibrillary acidic protein (human) | primarily in the central nervous system, affecting astrocytes, oligodendroglia, ependyma and some neurons; also periportal cells of the liver |  |
| 006474 | C57BL/6-Tg(Grik4-cre)G32-4Stl/J |
Grik4, glutamate receptor, ionotropic, kainate 4 (mouse) |
detectable at 14 days old in area CA3 of the hippocampus, and at 8 weeks of age, recombination is observed in nearly 100% of pyramidal cells in area CA3; recombination is also observed in other brain areas, but at distinctly lower frequencies |
 |
| 004692 | STOCK Tg(Hoxb7-cre)13Amc/J | Hoxb7, homeo box B7 (mouse) | mesonephric duct and its developmental derivatives (the Wolffian duct, the collecting duct epithelium of kidney and ureteral epithelium), ureteric bud and all ureteric bud epithelial cells; low levels of expression in the dorsal root ganglia and the spinal cord |  |
| 004782 | STOCK Tg(KRT14-cre)1Amc/J | KRT14, keratin 14 (human) | skin, the oral ectoderm including the dental lamina at 11.75 d.p.c., and the dental epithelium by 14.5 d.p.c. |  |
| 003771 | B6.Cg-Tg(Nes-cre)1Kln/J | Nes, nestin (rat) | primarily expressed in the central and peripheral nervous system by embryonic day 11 and a few isolated kidney and heart cells |  |
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Pcp2, Purkinje cell protein 2 (L7) (mouse) |
most Purkinje cells and some retinal bipolar neurons; small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue |
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| 006207 | Stock Tg(Pcp2-cre)1Amc/J |
Pcp2, Purkinje cell protein 2 (L7) (mouse) |
parasagittal domains of the cerebellum beginning at embryonic day 17 (E17); at E19, low level expression is observed in the most rostral lobe of cerebellum and expression broadens until all Purkinje cells express the transgene in adult mice |  |
| 006395 | Sim1, single-minded homolog 1 (Drosophila)(mouse) | expression is expected in all areas that endogenously express Sim1, including paraventricular hypothalamus and other parts of the brain |  | |
| 006143 | FVB/N-Tg(Thy1-cre)1Vln/J | Thy1, thymus cell antigen 1, theta (mouse) | neurons of the postnatal cortex and hippocampus |  |
