Cre Reporter Strains
Cre Reporter strains allow the user to assess the function (degree of excision) of an individual Cre line. These strains are engineered to express a reporter gene (such as lacZ or GFP) following the removal of a loxP-flanked STOP cassette, thus marking cell lineages that can be targeted with a given Cre line. Some lines also express a distinct reporter prior to Cre-mediated excision. The JAX repository provides a wide selection of cre reporter lines that incorporate distinct reporter molecules.
