Cre Strains for Neurobiology

The Jackson Laboratory Cre Repository distributes a large number of strains that specifically express Cre recombinase in the mouse brain, including genetically engineered mice from three large projects:

NIH Neuroscience Blueprint Cre Driver Network

Allen Institute for Brain Science Transgenic Mouse Project

Pleiades Promoter Project

All of the mice in these large sets have been characterized by the developing institution. Cre activity is also being detected using the high-throughput assay originally developed for the Allen Brain Atlas project to detect expression of a reporter gene in neural tissues. Non-target (i.e. non-neural) expression is also being characterized by The Jackson Laboratory repository staff. For initial data, see http://cre.jax.org/data.html

Below is a list of all the Cre strains for neurobiology currently available from the Jackson Laboratory Cre Repository.

Cre Recombinase Expression in Neural Tissue

Additional information:

JaxMice research tools for neurobiology.pdf