B6;129S6-Chattm1(cre)Lowl/J
B6;129S6-Chattm1(cre)Lowl/J males were mated to female Rosa 26 reporters (stock no 3474). Reporter (β-galactosidase) expression is expected in all cholinergic neurons. Primary reference.
Previously unreported β-gal expression observed in P7 kidney, and Adult kidney, ovary, testes and thymus.
β-galactosidase expression was assayed for E10.5 and E15.5 whole embryos, P0 pup, and P7 and Adult brain, heart, intestine, kidney, liver, lung, muscle, ovary, pancreas, spleen, testes and thymus.
| Age and Tissue |
Reporter Expression |
Image |
|
Embryonic Day 10.5
---Embryo |
Absent |
No images captured for negatively staining tissues. |
|
Embryonic Day15.5
---Head |
Strong-
Regionally Restricted |
 |
|
Embryonic Day 15.5
---Body |
Strong-
Regionally Restricted |
 |
|
Postnatal Day 0
---Head |
Strong-
Regionally Restricted |
 |
|
Postnatal Day 0
---Body |
Strong-
Regionally Restricted |
 |
|
Postnatal Day 7
---Brain |
Strong-
Regionally Restricted |
 |
|
Postnatal Day 7
---Kidney |
Moderate-
Regionally Restricted
Expression Not
Previously Reported. |
 |
|
Postnatal Day 7
---Intestine
---Heart
---Liver
---Lung
---Muscle
---Ovary
---Pancreas
---Spleen
---Testes
---Thymus |
Absent |
No images captured for negatively staining tissues. |
Adult
---Brain |
Strong-
Regionally Restricted |
 |
Adult
---Eye |
Moderate-
Regionally Restricted |
 |
Adult
---Kidney |
Strong-
Regionally Restricted
Expression Not
Previously Reported. |
 |
|
Adult
---Ovary |
Moderate-
Regionally Restricted
Expression Not
Previously Reported. |
 |
Adult
---Testes |
Strong-
Regionally Restricted
β-gal expression absent in testes but present in epididymis.
Expression Not
Previously Reported. |
 |
|
Adult
---Thymus |
Strong-
Regionally Restricted
Expression Not
Previously Reported. |
 |
|
Adult
---Heart
---Intestine
---Liver
---Lung
---Muscle
---Pancreas
---Spleen |
Absent |
No images captured for negatively staining tissues. |
Data and image acquisition by Caleb Heffner, B.S. Webpage content managed by Yashoda Sharma, Ph.D.
