Strain Name: B6.129-Tg(Pcp2-cre)2Mpin/J

Stock Number: 004146

B6.129-Tg(Pcp2-cre)2Mpin/J males were mated to female R26R reporter (stock no 3474). Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons. Small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue. Recombination is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth. Primary reference.

Data provided for E10.5 and E15.5 whole embryos, and P7 and Adult brain, heart, intestine, kidney, liver, lung, muscle, ovary, pancreas, spleen, testes and thymus.

Age and Tissue Reporter Expression Image
Embryonic Day 10.5
---Embryo		 Weak-
Scattered 		10.5 dpc embryo
Embryonic Day 15.5
 Very Weak-
Scattered 		15.5 dpc embryo
Postnatal Day 7
---Brain

Weak-
Scattered

 P7 Brain
Postnatal Day 7
---Heart/Thymus		 Moderate-
Scattered 		P7 heart and thymus
Postnatal Day 7
---Kidney		 Moderate-
Scattered 		P7 kidney
Postnatal Day 7
---Liver		 Moderate-
Scattered 		P7 Liver
Postnatal Day 7
---Lung

Very Weak-
Scattered

 P7 Lung
Postnatal Day 7
---Ovary		 Moderate in Ovary-
Scattered 		P7 Ovary
Postnatal Day 7
---Spleen/Pancreas		 Moderate in Pancreas-
Scattered 		P7 Spleen and Pancreas
Postnatal Day 7
---Testis		 Moderate-
Scattered 		P7 Testis
Adult
---Brain		 Strong-
Regionally Restricted 		Adult Brain
Adult
---Heart		 Moderate-
Scattered 		Adult Heart
Adult
---Kidney		 Moderate-
 Adult Kidney
Adult
---Liver		 Moderate-
Scattered 		Adult Liver

Adult
---Lung

 

Weak/ Moderate-
Scattered

 Adult Lung
Adult
---Ovary		 Weak/ Moderate-
Scattered 		Adult Ovary
Adult
---Pancreas

Moderate-
Scattered

 

 Adult Pancreas
Adult
---Testis and Epididymis		 Strong-
 Adult Testis


Data acquisition and weppage content management by Caleb Heffner, B.S.